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Egg retrieval with cryopreservation does not delay breast cancer treatment.

Madrigrano A, Westphal L, Wapnir I

Department of Surgery, Stanford University Medical Center, 300 Pasteur Dr, RM H3625, Stanford, CA 94305-5655, USA.

BACKGROUND: Infertility is a concern to young women diagnosed with breast cancer. Advances in fertility technology have made it possible to bank fertilized embryos. METHODS: Twenty-three women, ages 27 to 40 years, underwent stimulation/oocyte retrieval before the start of adjuvant therapies. Time intervals between retrieval and therapeutic procedures were analyzed. RESULTS: The average stimulation to egg retrieval was 11.5 days (range 9-20 d). The average time interval from first evaluation to oocyte retrieval was 33.3 days (range 10-65 d). Overall, the mean time from definitive surgery to initiation of chemotherapy was 46.8 days (n = 20). For 6 patients referred by surgeons, the mean time from fertility consult to retrieval was 48.8 days (range 16-118 d), and from definitive surgery to initiation of chemotherapy was 45 days (range 15-93 d). CONCLUSIONS: Egg retrieval cryopreservation can be integrated with breast cancer work-up and surgical procedures. Early referrals to a fertility specialist by surgeons will help patients' safeguard future childbearing.

Published 10 September 2007 in Am J Surg, 194(4): 477-81.
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